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Bioanalytical Services

Brains On-Line provides a wide range of bioanalytical services. We have state-of-the-art instrumentation for quantitative analysis of biomarkers, exogenous compounds and their metabolites in biological samples.

The following experimental configurations are supported:

  • HPLC – tandem mass spectrometry
  • HPLC – electrochemical detection
  • HPLC – fluorescence detection
  • RIA / ELISA

We offer:

  • Quantification of chemical concentrations in samples from in-house acquisition
  • Analysis of samples provided by our customers
  • Development of novel customized procedures for quantification
  • High quality assurance of all analysed data

Analytes:

  • Acetylcholine (pM range)
  • Amino acids (GABA, Glycine, Glutamate)
  • Monoamines (incl. NE, DA, 5HT) (pM range)
  • Histamine and Tele-Methyl Histamine (pM range)
  • DOPAC, 5-HIAA, HVA and MHPG
  • Kynurenines (pM range)
  • Adenosine, cAMP/cGMP (pM range)
  • d-Serine and l-Serine (nM range)
  • Glucose, lactate and pyruvate (pM range)
  • Arginine, Lysine, Ornithine, Putricine, Spermidine, Spermine
  • Ethanolamides
  • Exogenous compounds (pM range)
  • Glucocorticoids

All analysis may be performed in a wide range of biological matrices:

  • CSF samples
  • Brain microdialysate
  • Brain tissue samples
  • Plasma
  • Other tissue types
  • Other biological fluids

Quality Assurance

At Brains On-Line we adhere to the highest standards of quality and scientific integrity as is required in modern Research & Development. All our studies are carried out with in process Quality Assurance, and can be carried out in accordance with customer guidelines.



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