Bioanalytical Services
Brains On-Line provides a wide range of bioanalytical services. We have state-of-the-art instrumentation for quantitative analysis of biomarkers, exogenous compounds and their metabolites in biological samples.
The following experimental configurations are supported:
- HPLC – tandem mass spectrometry
- HPLC – electrochemical detection
- HPLC – fluorescence detection
- RIA / ELISA
We offer:
- Quantification of chemical concentrations in samples from in-house acquisition
- Analysis of samples provided by our customers
- Development of novel customized procedures for quantification
- High quality assurance of all analysed data
Analytes:
- Acetylcholine (pM range)
- Amino acids (GABA, Glycine, Glutamate)
- Monoamines (incl. NE, DA, 5HT) (pM range)
- Histamine and Tele-Methyl Histamine (pM range)
- DOPAC, 5-HIAA, HVA and MHPG
- Kynurenines (pM range)
- Adenosine, cAMP/cGMP (pM range)
- d-Serine and l-Serine (nM range)
- Glucose, lactate and pyruvate (pM range)
- Arginine, Lysine, Ornithine, Putricine, Spermidine, Spermine
- Ethanolamides
- Exogenous compounds (pM range)
- Glucocorticoids
All analysis may be performed in a wide range of biological matrices:
- CSF samples
- Brain microdialysate
- Brain tissue samples
- Plasma
- Other tissue types
- Other biological fluids
Quality Assurance
At Brains On-Line we adhere to the highest standards of quality and scientific integrity as is required in modern Research & Development. All our studies are carried out with in process Quality Assurance, and can be carried out in accordance with customer guidelines.
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