Behavior

Anxiety/Depression

• Forced Swim Test
• Tail Suspension Test
• Light/Dark Box

Cognition

• Novel Object Recognition (Natural Forgetting, Scopolamine Induced Deficits, Phencyclidine Induced Deficits)
• Contextual Fear Conditioning

Motor Activity/Coordination

• Home Cage Locomotor Activity
• Open Field Test
• Rotorod
• Grip Strength

Psychosis/Mania

• Apomorphine Rearing/Climbing
• Psychostimulant Induced Locomotion

Disease Models

• 6-hydroxydopamine Parkinson's Model
• Quinolinic Acid Huntington's Model
• Sub-chronic Phencyclidine

All behavior studies are carried out in mice or rats in our state of the art U.S. facility under review of an Institutional Animal Care and Use Committee. In addition to the array of pharmacologically validated assays, we strive to develop of new tests (in house or in collaboration with the sponsor). Given our expertise in microdialysis, all of our behavioral studies can be coupled to in vivo neurotransmitter monitoring via traditional microdialysis or with the use of biosensors.

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